CANLEISH

NETWORK – WIDE EVENTS

T6.2. Project workshops

Workshop W1: Metabolomics research in biomedical applications

Date: May 5, 2022 Place: EMU

Presentations from: UMI (3), IPT (1), ENCL (1), UU (1), UP (1), EMU (2), NVIS (1)

9:20–9:40Teerakiat Kerdcharoen (ENCL): “Digitalization of human body odor – Method, devices and application in digital health”
9:40–10:20Benachir Bouchikhi (UMI): “Breath and urine analysis: A promising tool for the detection of gas-analytes such as exhaled volatile organic compounds (VOCs)”
    
10:20–10:50Coffee break
    
10:50–11:10Lars Österlund (UU): “Chemoresistive nanoparticles sensors for gas-phase detection of chemical compounds in body fluids”
11:10–11:30Cristhian Duran (UP): “Development of multisensory perception systems for biomedical applications”
11:30–11:50Radu Ionescu (EMU): “Non-invasive staging of in-vitro mice embryos by means of volatolomics”
11:50–12:10Sergio Escalona (NVIS): “Impact of air pollution exposure on COVID-19 patients using a personalised gas sensing approach”
12:10–12:30Hafsa El Youbi (UMI): “Electrochemical sensing approach for the detection of ciprofloxacin residues in food and environment samples”
12:30 Lunch 

Physical Participants:

  1. Radu Ionescu (EMU)
  2. Chanaka Premathilaka (EMU)
  3. Hafsa El Youbi (UMI)
  4. Lisset Jaimes (UP)
  5. Theerapat Pobkrut (ENCL)
  6. Teerakiat Kerdcharoen (ENCL)
  7. Juta Kerdcharoen (ENCL)
  8. Tanthip Eamsa-ard (ENCL)
  9. Varanya Somaudon (ENCL)

Workshop W2 ’’Emerging diagnostic strategies for canine leishmaniasis’’

Date: November 24, 2022

Place: Faculty of Veterinary Medicine, Spiru Haret University, Bucharest, Romania

Presentations from project staff: USH (2), EMU (1).

Session I:

10:00 h – 10:05 h (1) Violeta Simion (USH) – Introduction

10:05 h – 10:15 h (2) Corina Traistaru and Theodor Diaconu (BioSystems) – BioSystems Introduction

10:15 h – 10:35 h (3) Ursachi Alexandra (USH) – “Analysis methods in dog leishmaniasis”

10:35 h – 10:55 h (4) Radu Ionescu (EMU) – “Diagnosing canine leishmaniasis through volatolomic techniques”

10:55 h – 11:15 h Coffee break

11:15 h – 11:35 h (5) Lixandru Madalina (USH) – “The hidden costs and opportunities of NTDs”

11:35 h – 12:25 h (6) Ana Isabel Palau (BioSystems) – “Emerging vector borne diseases in Romania: Leishmania and Ehrlichia”

12:25 h – 13:25 h Lunch

Session II: Workshop session

13:25 h – 14:55 h (1) Bruno Teixeira Dias (BioSystems) – Practical demonstration indirect immunofluorescence Assay

14:55 h – 15:00 h The awarding of diploma to all participants in this Workshop

Attendees: 58 participants

Workshop W3 ’’Animal diseases diagnosis with sensor systems’’

Date: Mayr 24, 2023

Place: University of Uppsala, Sweden

Session I

Presentations from:

14.30-14.50: (UP) Raquel Amanda Villamizar Gallardo, “Sensing and removing pathogenic microorganismos using nanomaterials”.

14.50-15.10: (EMU) R. Ionescu, R. Suschinel, H. Haick, “Volatile organic compounds analysis in vitro fertilisation’’

  1. (UMI): Benachir Bouchikhi, Analysis Of Volatile Organic Compounds In Exhaled Human Breath For Diseases Diagnosis By Using Electronic Nose Technology Combined With Pattern Recognition Methods’’
    1. (NVIS): Z. Haddi, X. Llauradó and N. Avellana, “Combination of electronic sensing system and AI for abnormal micturition detection’’

Session II – Discussions, summary & outlook: 1(USH), 1(EMU), 2(UMI), 1(NVIS), 1(IPT), 1(UCBET), 1(UP).

T6.3. Project training courses

T1. Canine Leishmaniasis

  • Organized by IPT online (https://meet.google.com/avj-xoic-spz), on 18/05/2021
  • Attendees: 2 (EMU) + 1 (NVIS) + 2 (UMI) + 8 (IPT) + 2 (UP) + 2 (ENCL) + 1 (Mahidol University, Thailand) + 1 (UU) + 4 (USH) + 3 (UCBET)
  • Talks:
  • Elias Barbria (IPT): “Leishmaniasis in the Tunisian context: Epidemiology, clinical, medical considerations and future trends”
  • Houaida Kbaier (IPT): “Leishmaniasis: Correlation between clinical polymorphism and intrinsic parasite factors?”
  • Dhafer Laouini (IPT): “Cutaneous Leishmaniasis: In Quest of Virulence Biomarkers”
  • Meher Sayhi (IPT): “Nanomaterials for leishmaniasis treatment and biosensing applications”
  • Fayçal Zeroual (UCBET): “Prevention, screening, diagnosis and treatment in Algeria”
  • Luis Carlos Peña (UP): “Prevention, screening, diagnosis and treatment in Colombia”
  • Viorel Andronie (USH) / Madalina Lixandru (USH): “Prevention, screening, diagnosis and treatment in Romania”
  • Madalina Lixandru (USH): “Canine Leishmaniasis management by veterinary clinics, dog rescue organizations and pet transport companies”

T2. Normative in the field of medical research with animals; Procedures for obtaining Ethics Committee approvals; The protocols from the veterinary medical environment. 

  • Organized by UCBET online, on 06/11/2021
  • Attendees: 1 (EMU) + 1 (NVIS) + 2 (UMI) + 2 (IPT) + 1 (UP) + 1 (ENCL) + 1 (UU) + 4 (USH) + 8 (UCBET)
  • Talks:

1. Zeroual Fayçal (UCBET): ‘’History of leishmaniasis’’

2. Nasri Hichem, Fayçal Zeroual (UCBET): ‘’Presentation and visit to the Research Laboratory on Biodiversity and Ecosystem Pollution of UCBET’’

3. Righi Souad (UCBET): ‘’Canleish parasitology team at UCBET (area of interest)’’

4. BOUCHEIKHCHOUKH Mehdi, DIB Loubna (UCBET): “Normative in the field of medical research with animals”.

5. LARABA Islem (UCBET): “Procedures for obtaining Ethics Committee approvals”.

6. MEGUINI Nadir (UCBET): “The protocols from the veterinary medical environment”.

7. SAIDANI KHALAF Kamel (UCBET): ‘’Clinic based canine leishmaniasis diagnostic’’

8. Lixandru Madalina (USH): ‘’Bioethical and Deontological priorities of leishmaniasis control programmes’’

9. Radu Magdalena (USH): ‘’Legislation and regulations concerning leishmaniasis in animals’’

T3. Metabolomics research in biomedical applications

Nezha El Bari (UMI): “Leishmaniasis in Morocco”
Amira Chouihi (IPT): “Usefulness of the TaqMan Real-Time PCR assays in the diagnosis of canine and human visceral leishmaniasis”
Teerakiat Kerdcharoen (ENCL): “Digitalization of human body odor – Method, devices and application in digital health”
Benachir Bouchikhi (UMI): “Breath and urine analysis: A promising tool for the detection of gas-analytes such as exhaled volatile organic compounds (VOCs)”
Lars Österlund (UU): “Chemoresistive nanoparticles sensors for gas-phase detection of chemical compounds in body fluids”
Cristhian Duran (UP): “Development of multisensory perception systems for biomedical applications”
Radu Ionescu (EMU): “Non-invasive staging of in-vitro mice embryos by means of volatolomics”
Sergio Escalona (NVIS): “Impact of air pollution exposure on COVID-19 patients using a personalised gas sensing approach”
Hafsa El Youbi (UMI): “Electrochemical sensing approach for the detection of ciprofloxacin residues in food and environment samples”

T4. Fabrication and characterisation of sensing nanomaterials

  • Organized by Uppsala University, Sweeden, May 23, 2023, hybrid.
  • Place: Ångström Laboratory, Uppsala University, Sweden
  • Zoom link: https://uu-se.zoom.us/j/64813686483?from=addon
  • Time zone: CET
  • Local chair: Lars Österlund (UU)
  • Attendees on-site: 1 (NVIS) + 1 (UMI) + 1 (UU) + 1 (UP) + 1 (EMU) online: 1(USH) + 1 (ENCL)

T4 included on-site training on nanomaterials fabrication (AGD, RF sputtering) and characterisation (SEM, TEM, XRD, XPS, FTIR and Raman) techniques. 

09:00 – 09:40 Lars Österlund (UU). Physical vapour deposition methods for

nanomaterials synthesis; Chemical vapour deposition methods for

nanomaterials synthesis; Nanomaterials characterization techniques

09:40 – 10.20 ENCL Characterization of sensing nanomaterials

10:30 – 12:00 Lars Österlund (UU) On-site laboratory training at Dept Solid State Physics

12:00 – 13:00 Lunch

13:00 – 15:00 Robert Langer lecture in Eva von Bahr Hall, Ångström Laboratory

T5. Sensing techniques for vapour samples analysis. Modules: Semiconductor gas sensors; Field effect transistors; Quartz crystal microbalance sensors; Surface acoustic wave sensors; Fibre optic gas sensors, Electrochemical cells.

T5 will include an operation demo of the UMI sensor systems based on semiconductor gas sensors and electrochemical cells.

Starting from 29/11/2023: Measurement of the dog volatile samples acquired by the partners from Tunisia and Algeria with the e-nose system built by University of Pamplona. This activity will be realised until all the dog samples will be analysed.

  • Organized by Moulay Ismail University, Meknes, Morocco, hybrid.
  • Place: Biosensors and Nanotechnology Group, Conference room, Faculty of Sciences

Google meet link: meet.google.com/bnx-oajd-oza

  • Project Chair: Violeta Simion (USH) – Primary Coordinator
  • Radu Ionescu (EMU) – Scientific Coordinator
  • Local chair: Nezha El Bari / Benachir Bouchikhi (UMI)

November 28, 2023

Chair: Dr Radu Ionescu

9.15-9.30 Prof. Nezha El Bari – Introducing the University of Moulay Ismail (UMI) – Research activities of Bio-Sensors and Nanotechnology Group

9.30-10.00 Prof. Janusz Smulko – Advances in 2D materials (graphene, MoS2) based field effect transistors for sensing applications

10.00-10.30 Dr. Zouhair Haddi – Electronic gas sensing system based on hybrid nanostructures of metal oxide and graphene for non-communicable diseases detection

10.30-11.30 – Group photo+coffee breah

Chair: Dr Mohamed Fethi

11.00-11.30 Dr Souad Bouhout – Leishmaniasis control program in Morocco

11.30-12.00 Dr Alassane Diouf – Development of an electrochemical sensor using MIP based on a gold screen-printed electrode for the detection of creatinine and glucose in human urine and saliva

12.00-14.30 – Lunch

Chair: Dr. Zouhair Haddi

14.30-14.14.45 Dr Aylen Lisset Jaimes-Mogollon – Electronic nose device for vapor samples analysis

14.45 – 15.00 PhD student Makhtar War – Operation demo of the UMI using electronic tongue for human urinary sample analysis.

15.00-15.15 PhD student Youssra Aghoudane – Operation demo of the UMI electrochemical sensors using MIP based on a gold screen-printed electrode

15.15 – 15.45 – Coffee break

15.45-17.45 – Visit of old Medina of Meknes

19.30 – Dinner

November 29, 2023

9.15-9.20 Opening Remarks – Prof Nezha El Bari

Moderator: Prof. Faycal Zeroual

9.20-10.00 Porf Benachir Bouchikhi – Chemiresitive Electronic Nose and Electronic Tongue Towards Analysis of Volatile Organic Compounds in Exhaled Breath and Human Urine

10.00-10.40 – Prof. Eduard Llobet – Recent advances in two-dimensional-inorganic material-based sensing technology toward health monitoring applications

10.40-11.00 – Coffee break

Moderator: Prof Nezha El Bari

11.00-11.20 – Dr Alassane Diouf – Operation demo of UMI electronic nose prototype based on semiconductor gas sensors

11.20-11.40 Dr Aylen Lisset Jaimes-Mogollon – Operation demo of Canleish e-nose system developed in Colombia

Moderator: Dr Radu Ionescu / Prof Nezha El Bari

11.40-12.00 Closing event

12.00-14.00 Lunch

14.30-18.00 Trip to Roman site of Volubilis and Moulay Idriss

  • Attendees:  (EMU: 1) +  (NVIS: 1) +  (UMI: 7)  +  (IPT: 1) +  (UP: 1) +  (ENCL: 1) +  (UU: 2) + 1 (USH) + (UCBET: 1)

T6: Modules: Features extraction from sensor responses; Unsupervised and supervised pattern recognition algorithms; Data clustering; Classification and quantification; “Data fusion algorithms.

Date: 25 April 2024

Place: On-site and Online Meeting Microsoft Teams, Meeting ID: 317 548 461 173 Passcode: qSSGef

Onsite: Location: Recinte Modernista Sant Pau

Address: C/ de St. Antoni Maria Claret, 167, 08025 Barcelona

  1. Atendees: onsite: 1 from NVIS, 3 from USH, 1 from EMU, 2 from UMI, 1 from UP, 1 from UU; online: 2 from USH, 1 from ENCL, 2 from UMI, 1 from UCBET, 1 from IPT, 1 from EMU.

15:00 – 16:00 Unsupervised and supervised pattern recognition algorithms (Mihailescu Marius [USH])

16:00 – 17:00 Gas Sensor Data Analysis: Results and discussions (Zouhair Haddi [NVIS])

17:00 – 18:00 CANLEISH Sensor Data Analysis of Volatile Organic Compounds of Canine 

Breath and Hair of IPT samples by UMI Team (Alassane DIOUF [UMI])

T7: Modules: What to know about the creation of a new company; Start-up and spin-off; Ways of funding your company; R&D versus commercial activity; Key exploitable results; Market study analysis; Contribution benefit matrix; Promote gender equality in entrepreneurship. The last module will be prepared in cooperation with USH.

Date: 25 April 2024

Place: On-site and Online Meeting Microsoft Teams, Meeting ID: 368 364 528 480 Passcode: g8tXbA

Onsite: Location: Recinte Modernista Sant Pau

Address: C/ de St. Antoni Maria Claret, 167, 08025 Barcelona

  1. Atendees: onsite: 1 from NVIS, 3 from USH, 1 from EMU, 2 from UMI, 1 from UP, 1 from UU, 1 from UCBET; online: 1 from USH, 1 from ENCL, 2 from UMI, 1 from IPT.

9:00 – 10:00 Product Roadmap from R&D to market Launch (Oxana Evseeva [NVIS])

10:00 – 11:00 An idea about how to you could monetise a new product (Cristea Constantin [USH])

11:00 – 11:30 Coffee break

11:30 – 12:30 “GC-MS and E-nose: a success story” (Tesfalem Welearegay [UU])

12:30 – 13:30 European R&D funding for SMEs: Challenges and Opportunities (Xavier Llauradó [NVIS])

13:30 – 14:00 Conclusions & Closing (Zouhair Haddi [NVIS])

T6.4. Project conferences

Date: 18/02/2022 – UP

Title: “Experience in European research projects” and CANLEISH project.

Place:  Auditorium “Club del Comercio”, Pamplona, Norte de Santander, Colombia. Hour: 10:30 am

Speakers: Radu Ionescu (EMU), Aylen Lisset Jaimes (UP)

Participants: – 25 face-to-face researchers and 42 researchers virtually of Antonio Nariño University, University of Manizales, University of Caldas, University of Valle, University of America, Simón Bolívar University, CIAF higher education, Polytechnic Corporation of the Atlantic coast, Caribbean University Corporation-CECAR, Polytechnic Corporation of the Atlantic Coast, Caribbean University Corporation-CECAR, Minuto de Dios University Corporation, Rafael Núñez University Corporation, Reformed University Corporation, Colombian School of Rehabilitation, Juan N. Corpas University Foundation, María Cano University Foundation, Envigado University Institution , Metropolitan Technological Institute – University Institution, SENA Magdalena.

Onsite project staff participants: 4 representatives from UP; 2 representatives from EMU

  1. 1st Annual project meeting, occurred 4 May 2022 EMU

Place: Estonian University of Life Sciences, Tartu, Estonia Modality: Hybrid

Zoom link: https://emu-ee.zoom.us/j/81678632034?pwd=MGdWQ05WLzVma2lUOHp0dlROOEJlQT09

  • KoM occurred 17 May 2021, USH

Place: Spiru Haret University, Bucharest, Romania

Modality: online, link: – https://meet.google.com/avj-xoic-spz, 21 participants.

  • 2nd Annual project meeting, occurred 28 November 2023, Moulay Ismail University, Meknes, Morocco, hybrid.

Place: Biosensors and Nanotechnology Group, Conference room, Faculty of Sciences. Google meet link: meet.google.com/bnx-oajd-oza

  • 3rd Annual project meeting, occurred 25 April 2024, NVIS, Barcelona, Spain.

Place: Online Meeting Microsoft Teams, Meeting ID: 326 269 244 50 Passcode: 5wvrVU

Onsite: Location: Recinte Modernista Sant Pau

Address: C/ de St. Antoni Maria Claret, 167, 08025 Barcelona